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Guidance® Prostatitis

Advanced diagnostic testing for patients with suspected acute or chronic prostatitis.

Guidance® Prostatitis combines the sensitivity of PCR for organism identification and antibiotic resistance gene detection with a unique technology called Pooled Antibiotic Susceptibility Testing (P-AST™) that accounts for interactions in polymicrobial infections that alter antibiotic resistance.

We offer two different sample types for Guidance® Prostatitis:

Post DRE Massage Urine Test

Semen Test

Guidance® Prostatitis uses molecular technology to identify fastidious bacteria and yeasts that are difficult to detect by culture. Post massage urine results available in less than one dayand semen results available within 48 hours.

Guidance® Prostatitis utilizes Pooled Antibiotic Susceptibility Testing (P-AST™), which accounts for bacterial interactions that occur in polymicrobial infections that may alter antibiotic resistance. Additionally, the report includes detection of antibiotic resistance genes.


The Guidance® Prostatitis report displays personalized therapy options to help speed the road to recovery.

The same Guidance® results you trust, from the comfort of home

Whether it’s busy schedules, limited mobility, or the patient was simply unable to leave a sample at the time of the office visit, incorporating Guidance® testing from the comfort of home can facilitate access to care as well as reduce the risk of exposure for both patients and providers. Additionally, at-home semen collection kits provide a comfortable alternative to traditional post-massage urine sample collection.

Patient Assessment
The provider determines if Guidance® UTI testing is appropriate for the patient.

One step ordering
The provider completes a Guidance® UTI test requisition and faxes it to Pathnostics.

Signature service
Pathnostics will call each patient to review specimen collection instructions, coordinate same-day pickup for overnight shipping, and answer questions about the process.

Fast turnaround time
Once received at the lab, Guidance® UTI home kits have the same less than one day† turnaround you’ve come to depend on with our in-office results.


  • Acinetobacter baumannii
  • Actinotignum schaalii
  • Aerococcus urinae
  • Alloscardovia omnicolens
  • Candida albicans
  • Candida auris
  • Candida glabrata
  • Candida parapsilosis
  • Citrobacter freundii
  • Citrobacter koseri
  • Corynebacterium riegelii
  • Enterococcus faecalis
  • Enterococcus faecium
  • Escherichia coli
  • Klebsiella oxytoca
  • Klebsiella pneumoniae
  • Morganella morganii
  • Mycoplasma hominis
  • Pantoea agglomerans
  • Proteus mirabilis
  • Providencia stuartii
  • Pseudomonas aeruginosa
  • Serratia marcescens
  • Staphylococcus aureus
  • Streptococcus agalactiae
  • Ureaplasma urealyticum
  • Coagulase-negative staphylococci*
  • Viridans group streptococci†
  • Enterobacter group‡
    Positive results presented with E. coli, Klebsiella, Enterocobacter, Citrobacter, Proteus, Acinetobacter, or Pseudomonas are detected.
    MRSA phenotypic assay will be performed when Staphylococcus aureus and the mecA gene are detected.

*Coagulase-negative staphylococci: Staphylococcus epidermidis, Staphylococcus haemolyticus, Staphylococcus lugdunenesis, Staphylococcus saprophyticus

Viridans group streptococci: Streptococcus anginosus,
Streptococcus oralis, Streptococcus pasteuranus

‡Enterobacter group: Klebsiella aerogenes (formally known as Enterobacter aerogenes), Enterobacter cloacae

We leverage a dual assessment—genotype resistance and Pooled Antibiotic Susceptibility Testing (P-AST™)—to uncover more effective, personalized therapy options.

Pooled Antibiotic Susceptibility Testing (P-AST™) includes:
  • Ampicillin (PO/IV)
  • Amoxicillin/Clavulanate (PO)
  • Cefepime (IV)
  • Ceftazidime (IV)
  • Ceftriaxone (IM/IV)
  • Ciprofloxacin (PO/IV)
  • Fosfomycin (PO/IV)
  • Gentamicin (IM/IV)
  • Levofloxacin (PO)
  • Meropenem (IV)
  • Piperacillin/Tazobactam (IV)
  • Sulfamethoxazole/Trimethoprim (PO/IV)
  • Tetracycline (PO)
  • Ampicillin
  • Carbapenem
  • Extended Spectrum Beta-Lactamase
  • Methicillin
  • Quinolinone/Fluoroquinolone

Watch our collection instruction videos for collecting a voided post prostatic massage urine or semen sample.

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1. Jarvi K, Lacroix J-M, Jain A, et al (1996) Polymerase chain reaction-based detection of bacteria in semen**Supported by grants from The Physicians’ Services Incorporated Foundation,
Toronto, Ontario, Canada (K.J, D.H., and M.W.M.). A Roscoe-Reid Graham Scholarship in Surgical Science and a Canadian Urology Association Scholarship, Toronto, Ontario, Canada is held
by K.J. Fertil Steril 66:463–467.

†When specimen collected as instructed

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