Cervical Risk Stratification

GYN Cytology
High Risk.

A powerful tool for stratifying borderline Pap test results — surfacing which patients with borderline abnormal cells are most likely to progress.

Routine Pap screening tells you what's there. The Gyn Cytology HR test tells you what's likely next — helping clinicians act on the 10% of borderline results that actually need follow-up.

How the test works

Routine Pap, sharper signal,
clearer next step.

10%
borderline-result patients

Indication

All women undergoing a routine Pap screen benefit from Gyn Cytology HR. The largest impact is on patients with borderline results — where the test helps differentiate progression-likely from likely-benign cases.

Where it matters most

Gives the clinician a direction for borderline Pap results, not just a re-read.

1
specimen, 6-week stability

Sample method — Pap test

Specimen collected from the cervix into a ThinPrep PreservCyt vial — used for cytology, FISH, and molecular testing. Best to send the same day; stable up to 6 weeks at room temperature in the supplied vials.

Logistics-friendly

One vial, multiple modalities, room-temperature transport in the Pap kit.

Frequently Asked Questions

Everything your team typically asks.

Who benefits most from the Gyn Cytology HR test?

All women undergoing routine Pap screening benefit. The patients who benefit most are those who receive a borderline test result — the test stratifies which of those cases warrant closer monitoring or earlier intervention.

How is a sample collected and transported?

Sample is collected from the cervix into a ThinPrep PreservCyt vial — used for cytology, FISH, and molecular testing. Pathnostics supplies the vials, which stabilize samples for up to 6 weeks at room temperature. Best practice is to send the sample to the lab the same day it's collected; the sample must arrive within the 6-week window.

What markers does the test use?

The test employs several markers to assess cervical cell health and provide predictive information. The marker panel is documented in detail in the reference PDF below.

View Markers (PDF) →

How does this differ from Cytology / High Risk HPV?

Both are women's-health cytology tests, but they serve different roles. Gyn Cytology HR focuses on stratifying borderline Pap results. Cytology / High Risk HPV is a broader screening panel that pairs ThinPrep cytology with the FDA-approved Aptima® HPV assay (and optionally Aptima Combo 2® for chlamydia / gonorrhea).

Request more information about GYN Cytology HR.

Connect with a representative to learn how the test can support borderline Pap stratification across your practice.