Cervical Screening Panel

Cytology &
High Risk HPV.

ThinPrep cytology paired with the FDA-approved Aptima® HPV assay for high-risk HPV detection — with optional Aptima Combo 2® for chlamydia and gonorrhea.

The Pap smear is a screening procedure that aids in the detection of cancer and its precursors — not the sole means of detecting cervical cancer. Pairing it with molecular HPV testing strengthens the screening signal.

How the panel works

One ThinPrep sample,
three lines of evidence.

24–65
indicated patient age

Indication

Indicated for cervical cancer screening for women between the ages of 24 and 65, in line with current screening guidelines.

Where it fits

Routine screening — cytology plus molecular HPV strengthens the signal.

1
ThinPrep sample

Sample method

A single ThinPrep specimen supports cytology, the Aptima® HPV assay, and the Aptima Combo 2® assay — one collection, multiple molecular reads.

Workflow-friendly

Same vial for cytology and the molecular panels — no second draw.

Clinical Utility

Three assays, one ThinPrep workflow.

ThinPrep cytology

The cytology read includes specimen source, specimen adequacy, descriptive findings, and additional findings — with recommended follow-up steps documented for the clinician.

Aptima® HPV assay

An FDA-approved in vitro nucleic-acid amplification test detecting several high-risk HPV types. Positive results indicate qualitative detection of E6/E7 viral messenger RNA (mRNA) of any one or more high-risk HPV types in the cervical specimen. Negative results indicate HPV E6/E7 mRNA was not detected.

High-risk HPV types detected: 16, 18, 31, 33, 35, 39, 45, 58, 59, and 68.

Aptima Combo 2® assay

An FDA-approved assay that detects the presence of Chlamydia trachomatis and Neisseria gonorrhoeae. Positive results diagnose chlamydia and/or gonococcal urogenital disease.

Frequently Asked Questions

Everything your team typically asks.

Who is this panel indicated for?

Indicated for cervical cancer screening for women between the ages of 24 and 65. Note: the Pap smear is a screening procedure, not the sole means of detecting cervical cancer — results should be interpreted alongside clinical context.

What sample is required?

A single ThinPrep cervical specimen supports cytology, the Aptima® HPV assay, and the Aptima Combo 2® assay — one vial, multiple reads.

Which high-risk HPV types are detected?

HPV types 16, 18, 31, 33, 35, 39, 45, 58, 59, and 68. Detection is based on E6/E7 viral mRNA via the FDA-approved Aptima® HPV assay.

How does this differ from GYN Cytology HR?

Both are women's-health cytology tests. Cytology / High Risk HPV is a broader screening panel that pairs ThinPrep cytology with the Aptima® HPV and Aptima Combo 2® assays. GYN Cytology HR focuses on stratifying borderline Pap results — a different question, with a different marker panel.

Request more information about Cytology / High Risk HPV.

Connect with a representative to learn how the panel fits into your cervical screening workflow.